Saturday, October 3, 2009

Pseudomembranous Colitis (Ischemic Colitis)

Ischemic Colitis

Pseudomembranous colitis (PMC) is an acute colitis characterized by the formation of an adherent inflammatory membrane (pseudomembrane) overlying sites of mucosal injury.

PMC is a well recognised cause of diarrhea in patients following a course of broad-spectrum antibiotic therapy. Clostridium difficile infection is the most important infectious cause of PMC.

Ampicillin, clindamycin, and cephalosporins are the most common antibiotics associated with this disease in children. Pseudomembranous colitis is rare in infants younger than 12 months old because they have protective antibodies from the mother and because the toxin does not cause disease in most infants.

Most cases of pseudomembranous colitis happen when a person is in the hospital, because the bacteria can spread from one patient to another.

Risk factors include:

• Advanced age
• Antibiotic use
• Chemotherapy
• Medications that suppress the immune system
• Recent surgery
• Personal history of pseudomembranous colitis

Ischemic Colitis

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2 comments:

Product Designers Delhi said...

Very informative, keep posting such good articles, it really helps to know about things.

GST Training Delhi said...

Thanks for sharing. I hope it will be helpful for too many people that are searching for this topic. Keep posting and keep this forum a great place to learn things.

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